ASSOCIATION OF PATTERN OF MYOCARDIAL FIBROSIS WITH ADVANCED AND EARLY HEART FAILURE

Abstract

Background: The cardiomyopathies are defined as “hetrogenous group of diseases of the myocardium associated with mechanical or electrical dysfunction that usually (but not invariably) exhibit inappropriate ventricular hypertrophy or dilatation and are due to variety of causes that frequently are genetic. They usually present clinically with heart failure.

Methods: The cross sectional hospital based study was conducted in the Department of Radiodiagnosis in patients with heart failure with LVEF (Left Ventricular Ejection Fraction) of <45% without RWM(Regional Wall Motion)  abnormality on echocardiography evaluated in department of cardiology at IGMC, Shimla over a period of one year.

Results: The myocardial fibrosis was seen in the 10 (47.62%) patients of advanced heart failure and 6(35.29%) patients of early heart failure with insignificant P value of 0.52 and odd ratio of 1.64.The subendocardial myocardial fibrosis in coronary territory was seen in the 3(14.29%) patients of advanced heart failure and 2(11.76%) patients of early heart failure with insignificant P value of 1.00 and odd ratio of 1.24.

Conclusion: The association of pattern of myocardial fibrosis with advanced and early heart failure was found statistically Insignificants

Keywords: MRI, Myocardial,  Heart failure.