https://www.ijmbs.info/index.php/ijmbs/issue/feedInternational Journal of Medical and Biomedical Studies2025-12-22T13:44:45+00:00IJMBSeditor@ijmbs.infoOpen Journal Systems<p><strong>Aims and Scope</strong></p> <p style="text-align: justify;">International Journal of Medical and Biomedical Studies (IJMBS) is an international, peer-reviewed, open access, online journal dedicated to the rapid publication of full-length original research papers, short communications, invited reviews, Case studies and editorial commentary and news, Opinions & Perspectives and Book Reviews written at the invitation of the Editor in all areas of the Medical and Biomedical Studies.</p> <p style="text-align: justify;">International Journal of Medical and Biomedical Studies is an academic journal which aims to publish complete and reliable source of information in the field of medical research providing the fundamental knowledge for further research. <em>IJMBS</em> commits to publish the results of researches in medical practice, risk factors and preventive medicine, safety and effectiveness of treatments, and diagnostic tools that are used to treat any disease. Our journal aims to attract an international audience of Medicine professionals enthusiastic to the most updated and substantial medical progress through the full spectrum of medical research.</p> <hr /> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Medical Studies|| Biomedical Studies || </strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Anatomy, Physiology, Anesthesia,<strong> </strong>Biochemistry, Molecular Biology, Cell biology, Genetics, Hematology, Pathology, Immunology, Microbiology, Virology, Parasitology, Surgery, Dental Sciences, Sports Physiology, Histopathology, Toxicology and all major disciplines of Biomedical Sciences, Pharmacokinetics, Molecular Drug Design, Phytochemistry, Toxicology, Biomedical Analysis, Clinical Research, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology, Agriculture, Herbal Medicine, Orthopaedics and all major disciplines of Medical and Biomedical Studies.</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Articles are published as they are accepted and are freely available on the journal’s website to facilitate rapid and broad dissemination of research findings to a global audience.</span></span></p> <hr /> <p style="text-align: justify;"><strong style="font-size: 14px; font-family: 'lucida sans unicode', 'lucida grande', sans-serif; text-align: justify;">Top Reasons for publication with us</strong></p> <hr /> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Quick Quality Review:</strong> The journal has strong international team of editors and reviewers, Rapid Decision and Publication</span></span></p> <hr /> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong style="font-size: 14px; font-family: 'lucida sans unicode', 'lucida grande', sans-serif;">Other features:</strong> DIDS and DOI: Assigned and Implemented the Open Review System (ORS).</span></span></p> <hr /> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Important Notice:</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Author can now directly send their manuscript as an email attachment to <strong><span style="color: #008000;">editor@ijmbs.info</span></strong></span></span></p> <hr /> <p> </p>https://www.ijmbs.info/index.php/ijmbs/article/view/3151Study of Platelet Indices in Patients of Chronic Myeloproliferative Disorders2025-12-22T13:44:45+00:00Md. Zeeshan HaiderEDITOR@IJMBS.INFOShuchismitaEDITOR@IJMBS.INFOIffat JamalEDITOR@IJMBS.INFOVijayanand ChoudharyEDITOR@IJMBS.INFOBipin KumarEDITOR@IJMBS.INFO<p style="font-weight: 400;"><strong>Background:</strong> Chronic myeloproliferative disorders (CMPDs), including Polycythemia Vera (PV), Essential Thrombocythemia (ET), and Primary Myelofibrosis (PMF), are clonal hematopoietic stem cell disorders characterized by dysregulated proliferation of myeloid lineages. Platelet abnormalities are central to their pathophysiology, predisposing patients to both thrombotic and hemorrhagic complications. Automated hematology analyzers provide platelet indices such as mean platelet volume (MPV), platelet distribution width (PDW), platelet-large cell ratio (P-LCR), and plateletcrit (PCT), that can serve as inexpensive biomarkers for diagnosis and prognostication.</p> <p style="font-weight: 400;"><strong>Methods:</strong> A prospective observational study was conducted in the Department of Hematology/Pathology, Indira Gandhi Institute of Medical Sciences (I.G.I.M.S., from April 2020 to June 2022. A total of 160 patients diagnosed with CMPDs according to the World Health Organization (WHO) 2016 criteria were enrolled. Demographic, clinical, and laboratory data were collected. Platelet indices were recorded using a fully automated hematology analyzer. Data were analyzed using ANOVA, t-tests, chi-square, and correlation analyses, with p < 0.05 considered significant.</p> <p style="font-weight: 400;"><strong>Results:</strong> ET was the most common CMPD (45%), followed by PV (33.8%) and PMF (21.2%). ET patients exhibited significantly higher platelet counts compared to PV and PMF (p < 0.001). PMF patients demonstrated the highest MPV, PDW, and P-LCR values, reflecting abnormal megakaryopoiesis. Thrombotic events occurred in 16.3% of patients and correlated with elevated MPV and PDW, while bleeding events (8.8%) were associated with increased PDW and reduced PCT.</p> <p style="font-weight: 400;"><strong>Conclusion:</strong> Platelet indices differ significantly among CMPD subtypes and were associated with vascular complications. They represent cost-effective, readily available markers that may complement molecular and histological investigations for diagnosis, risk stratification, and disease monitoring in CMPDs.</p> <p><strong>Keywords:</strong><span style="font-weight: 400;"> Chronic myeloproliferative disorders, platelet indices, thrombocytosis</span></p>2025-12-22T00:00:00+00:00Copyright (c) 2025 International Journal of Medical and Biomedical Studies