The CLINICOPATHOLOGICAL SPECTRUM OF ORAL SQUAMOUS CELL CARCINOMA AMONG TOBACCO CONSUMERS: AN INSTITUTIONAL STUDY

Abstract

Background: Oral squamous cell carcinoma (OSCC) constitutes 90% of all oral malignancies. Tobacco products, viral infections and additional risk factors are common etiological elements for this tumor.

Objective: The aim of this study is to analyze the clinicopathological and sociodemographic features of patients diagnosed with oral squamous cell carcinoma.

Material and Methods: Histologically confirmed 35 OSCC cases were selected for study. The clinicopathological data was obtained from patients and analyzed using SPSS software version 20.

Results: Majority of cases was men and diagnosed with disease during fourth decade of life. Buccal mucosa was the common site while gutka chewing was observed as leading habit among our cases. Also, stage II and moderate histological differentiation was predominant among prognostic indicators of OSCC.

Conclusion: Our data suggested that men, gutka consumers and early onset of disease are more prevalent characteristics in oral squamous cell carcinoma cases from our population. Most tumors classically affected buccal mucosa and late diagnosis seems to be common among our cases.

Keywords: Malignancy, Squamous Cell Carcinoma, Oral Cavity, Tobacco