TO FIND OUT AN APPROPRIATE CUT-OFF VALUE OF HUMAN b-HCG LEVELS IN CERVICOVAGINAL SECRETIONS FOR PREDICTION OF PRETERM DELIVERY

Abstract

Background: Preterm birth is the leading cause of neonatal morbidity and mortality worldwide and account for 75% of neonatal deaths and 50% of long term morbidity, including respiratory disease and neurodevelopment impairment.

Methods: Hospital based descriptive type of Observational study conducted at Department of Obstetrics and Gynaecology. SMS Medical College and Hospital, Jaipur (Raj.)

Results: ROC curve analysis was performed to determine the optimal cut-off values of significant variables (b-hcg harmone) detected between the two groups. A 19.05 mIU/ml (Positive if greater Than or Equal To) area under the curve (AUC = 0.906) optimal cut- off value of b-hcg harmone, with a sensitivity of 86% and a specificity of 97.1%, was determined with SE 0.036. This level is good to use as a diagnostic test.

Methods:    ?-HCG test is good and ?-hcg has high sensitivity and specificity so can be used as a diagnostic test for preterm labor.

Keywords: ?-HCG, Sensitivity, Specificity, Diagnostic.