TO EVALUATE THE ROLE OF INTRATHECAL HATG AND ITS COMPARISON WITH INTRAVENOUS AND INTRAMUSCULAR HATG IN TREATMENT OF TETANUS

Abstract

Background: Tetanus is a vaccine-preventable disease that continues to occur despite several decades of sustained global health programs. Recently outbreaks of tetanus have been reported after natural disasters such as tsunamis and earthquakes.

Methods: The present study was carried out among 30 patients of tetanus irrespective of age, sex and severity, admitted in P.B.M. Hospital, Bikaner.

Results: Overall mortality was 30% in present study. Out of 10 patients in each group one in group I, 4 in group II and 4 in group III expired respectively. So the mortality was 10% in group I, 40% in group II & III. In mild tetanus mortality was nil in all groups. In moderate tetanus mortality was 9.9%. All patients of moderate tetanus in group I and II survived. In group III mortality in moderate tetanus patients was 20%. In severe tetanus patients over all mortality was 53.3%, in group I 25%, in group II and 50% and in group 10% respectively.

Conclusion- Intrathecal HTAT is safe and effective treatment.

Keywords: Intrathecal, Intravenous, Mortality, HTAT.