EFFECT OF HEPATITIS-B VIRUS CO-INFECTION ON CD4 CELL COUNT AND LIVER FUNCTION OF HIV INFECTED PATIENTS

Abstract

Background: Liver disease caused by chronic hepatitis B virus (HBV) is emerging as a significant cause of morbidity and mortality among human immunodeficiency virus (HIV)-infected individuals.

Methods: This study is conducted in J. L. N. Medical College & Associated groups of Hospitals patients attending from ICTC (G). 500 samples are taken randomly from January 2018 to June 2018

Results: In the co-infected patients, ALT, AST and ALP were higher than normal. The mean serum level of ALT, AST and ALP were significantly higher in the co infected patients than in the HIV mono infected patients. The mean level of CD4+ count was significantly lower in the co infected patients than in the HIV mono infected patients.

Conclusion: Hepatitis B virus co-infected HIV positive patients are more likely to have abnormal liver function test than the mono-infected patients.

Keywords: HIV, Hepatitis B, CD4 count, co-infection