COMPARISON OF PARACETAMOL AND IBUPROFEN FOR THE ACUTE TREATMENT OF MIGRAINE IN CHILDREN AGED 6-12 YEARS

Abstract

Background: Migraine is a prevalent condition in pediatric populations, significantly affecting quality of life. While various treatment options are available, the efficacy and safety of commonly used analgesics like paracetamol and ibuprofen remain debated.

Objective: This study aims to compare the effectiveness and safety of paracetamol and ibuprofen in the acute treatment of migraine in children aged 6-12 years.

Material and Methods: A total of 60 pediatric patients diagnosed with acute migraine were included in this prospective study conducted in the Department of Pediatrics at a tertiary care hospital. Patients were randomly assigned to receive either paracetamol (15 mg/kg) or ibuprofen (10 mg/kg). The primary outcome was the reduction in pain intensity measured on a visual analogue scale (VAS) after 2 hours. Secondary outcomes included side effects and the need for rescue medication.

Results: Ibuprofen was found to be significantly more effective than paracetamol in reducing pain intensity. Side effects were minimal and comparable between both groups.

Conclusion: Ibuprofen is more effective than paracetamol for the acute treatment of migraine in children aged 6-12 years, with a favorable safety profile.

Keywords: Migraine, Paracetamol, Ibuprofen, Pediatrics, Acute Treatment.