Histopathological Analysis of Gastrointestinal Polyps: A Yearlong Study at a Tertiary Care Center

Abstract

This retrospective study was conducted at a tertiary care institute from January to December 2023. The study aimed to evaluate the range of histological characteristics seen in gastrointestinal polyps. By employing Hematoxylin and Eosin (H&E) stained slides, a total of 62 cases were examined in order to categorise polyps according to age, gender, location, and histological type. The results indicated that adenomatous polyps were primarily located in the large intestine, while hyperplastic polyps were more prevalent in the stomach. Additional forms that were detected include hamartomatous, juvenile, fundic gland, inflammatory fibroid, fibroepithelial, retention polyps, and a single case of familial polyposis coli. The study observed a male-to-female ratio of 0.9:1, with the highest number of cases occurring in the age bracket of 61-70. The findings emphasize the significance of differentiating between neoplastic and non-neoplastic polyps, especially because neoplastic polyps can progress through an adenoma-carcinoma sequence.

Keywords: Gastrointestinal polyps, adenomatous polyp, hyperplastic polyp