ANALYSIS OF LIVER FUNCTION TEST RESULTS IN PATIENTS UNDERWENT CHOLECYSTECTOMY

Abstract

Introduction: Open cholecystectomy can treat gallstones faster and with fewer complications. Studies suggest fewer post-surgery complications than open cholecystectomy. Some say surgery affects liver enzyme levels temporarily. Potential biliary injuries must be identified and treated quickly. Due to advances, outpatient open cholecystectomy generally raises liver function tests. Impaired testing does not always indicate open surgery. Research examines whether liver function should be measured before and after open cholecystectomy.

Aims and Objective: To assess alterations in liver function following cholecystectomy by analyzing the results of liver function tests in patients.

Methods: A one-year prospective cross-sectional study on open cholecystectomy patients measured ALT/SGPT (<40 UL?1), serum bilirubin (<1 mg/dL), and serum ALP (60-170 UL?1) before and after operation Pre-operative measurements were taken once, and post-operative measures were on Day 1 and Day 3 (if LFT rose). CO2 insufflation, pneumoperitoneum duration, intra-abdominal pressure, and anaesthesia were recorded. The investigation sought substantial liver enzyme alterations and age-LFT correlations.

Results: The majority (25.00%) of the 120 patients undergoing open cholecystectomy were male and in the 31-40 age bracket. Results from liver function tests showed that people between the ages of 51 and 70 had significantly higher levels of bilirubin and transaminase compared to younger age groups. The needs to take into account both age and specific liver indicators for a thorough evaluation of health is highlighted by the fact that there are age-specific patterns of liver function abnormalities.

Conclusion: The study concluded that the levels of bilirubin, SGOT, SGPT, ALP, and SGOT elevated considerably post open cholecystectomy.

Keywords: Opencholecystectomy, anaesthesia, liver function, gallstones.