Protective Effects of Sida Veronicaefolia against RIF+INH Induce Hepatotoxicity in Experimental Animals

Authors

  • Vidhi Jain Research Scholars, Department of Pharmacy, SunRise University, Alwar, Rajasthan
  • Ajay Kumar Research Scholars, Department of Pharmacy, SunRise University, Alwar, Rajasthan
  • Shilpi Mishra Research Scholars, Department of Pharmacy, SunRise University, Alwar, Rajasthan.
  • Manmeet Singh Saluja Professor, Department of Pharmacy, SunRise University, Alwar, Rajasthan

DOI:

https://doi.org/10.32553/ijmbs.v6i11.2628

Abstract

In the current research, rats will be given RIF+INH (hepatotoxic), and the hydoethanol (HEESV) extract of the leaves of Sida veronicaefolia will be tested to see how well it protects the rats' livers from damage caused by the RIF+INH. Liver function tests and serum profiles were used to provide an estimate of the hepatoprotective effects of HEESV at a dose of 500 mg/kg. According to the findings, the extracts of Sida veronicaefolia not only provide a strong hepatoprotective impact by lowering blood levels of serum transaminases (SGPT and SGOT), alkaline phosphate, and total bilirubin, but they also considerably enhance the levels of total protein. The effects of HEESV were quite similar to those of the standard medication silymarin.

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Published

2022-11-16

How to Cite

Jain, V., Kumar, A. ., Mishra, S. ., & Singh Saluja, M. . (2022). Protective Effects of Sida Veronicaefolia against RIF+INH Induce Hepatotoxicity in Experimental Animals. International Journal of Medical and Biomedical Studies, 6(11). https://doi.org/10.32553/ijmbs.v6i11.2628

Issue

Vol. 6 No. 11 (2022)

Section

Articles

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Copyright (c) 2022 International Journal of Medical and Biomedical Studies

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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