TO STUDY THE TIME TREND OF NORMALIZATION OF LACTATE THAT FAVORS SURVIVAL IN MAJOR TRAUMA AND SEPSIS.

Abstract

Background:

A prospective, non-intervention study was undertaken To study the time trend of normalization of lactate that favors survival in major trauma and sepsis in the Department of Surgery, Index Medical College Hospital and Research Centre, Indore, M.P., India for 01 year time duration. A total of 50 patients were included into study.

Result: persistent higher LACTATE levels in non-survivors in major trauma and sepsis after 48 hours. And gradually decrease level in survivor. Thus, rising serum lactate levels suggest early prediction of shock and mortality.(p values less than 0.01)

Above table suggest that rising serum lactate levels predict mortality in trauma and sepsis irrespective of age of patients. Because results are statistically insignificant (p > 0.01)

Conclusion:  Lactate values probably need to be followed for longer periods in critical patients even when they have tided over the present crisis. The utility of regular lactate analysis in these patients would depend on factors such as availability and cost of test also. There are no existing studies to support the above premise.

Keywords: Normalization, Lactate, Survival, Trauma & Sepsis