SERUM ALBUMIN LEVEL IN PERSISTENT ORGAN FAILURE IN ACUTE PANCREATITIS

Abstract

Introduction: The research emphasises on the association bond of Serum Albumin Level used as a marker for diagnosis of Persistent Organ Failure in Acute Pancreatitis.

Material and Methods: The samples for the study were collected from the central lab, out-patient department and in-patient department of Department of Biochemistry, adult patients suffering from Acute Pancreatitis correlated to tropical medicinal stream and Gastroenterology Rabindranath Tagore Medical College, Udaipur, Rajasthan  The research was carried out on a total of 100 patients for  1 year  which  were satisfying   Atlanta criteria  for Acute Pancreatitis will be diagnosed based on the following symptoms; elevated serum amylase, and lipase levels, that is greater than the normal limit, findings associated with the characteristics of the radiological findings. Also, with the abdominal computerized ultrasonography and tomography

Results: In the present research, albumin always descends obviously in AP patients with POF (p?<?0.05). The AUC under ROC line is 0.869. Albumin has been proved as an excellent marker of POF in AP. However, no previous study has researched into the association between albumin and incidence of POF in AP. Therefore, this study is the first time to show that the reduction of serum albumin is significantly associated with increased risk of POF in AP.

Conclusion: Thus it can be concluded that serum albumin on admission is independently associated with POF in AP. The study suggests that albumin is a valuable tool for a rapid assessment of POF in patients with AP.

Keywords: Serum Albumin, Persistent Organ Failure, Acute Pancreatitis