FASTING LIPID PROFILE AND DISEASE SEVERITY IN SEPSIS PATIENTS

Abstract

Background: During an infection and inflammation many cytokines are released. This produces many changes in plasma lipids and lipoprotein concentration.

Methods: This was a prospective observational study. Patients with age greater than 18 years and satisfying the criteria for sepsis according to International guidelines for management of severe sepsis and septic shock 2016 were included.

Results: The study population comprised 16 males and 14 females with mean age of 57.2 ± 7.21 years. Both groups were comparable. Cholesterol, HDL and LDL level difference in septic and control was stastically significant.

Conclusion: In ICU setting, measurement of cholesterol values has been shown to improve risk prediction, and inclusion of lipid values in clinical risk assessment scores of critically ill patients has been advocated.

Keywords: Lipid profile, Sepsis, Cholesterol.