STUDY THE RELATION BETWEEN SERUM SODIUM AND THE MODEL FOR END-STAGE LIVER DISEASE SCORE IN PATIENTS WITH LIVER CIRRHOSIS AT TERTIARY CARE HOSPITAL BIKANER, RAJASTHAN

Abstract

Background: Liver cirrhosis was common problem in india. The aim of the study was to evaluate the prevalence of hyponatremia in liver cirrhosis and the correlation between serum sodium and the Model for End-Stage Liver Disease (MELD) score in patients with liver cirrhosis.

Methods: We prospectively collected data of 100 patients of chronic liver disease hospitalized in department of General Medicine Sardar Patel medical college, Bikaner.  

Results: Mean age of patients was 52.11±14.63 years and consisted of 78 men and 22 women. The mean MELD score, 14.21±4.98 and mean serum sodium concentration, 133.21±8.24 mmol/L. Serum sodium values were strongly associated with severity of cirrhosis, assessed by child Pugh class and MELD score.

Conclusion: Hyponatremia is a common problem in liver cirrhosis, especially advanced cirrhosis. The study showed that there is an association between hyponatremia and the presence of certain complications of liver cirrhosis. Also hyponatremia was associated with a higher severity of cirrhosis assessed by MELD scores. 

Keywords: Child pugh class, Liver cirrhosis, MELD score, Hyponatremia