DIAGNOSTIC EFFICACY OF ENDOMETRIAL ASPIRATION CYTOLOGY WITH HISTOPATHOLOGICAL CORRELATION

Abstract

Background: To assess the diagnostic accuracy of endometrial aspiration technique and to compare the cyto-morphology of aspirated smears with histopathology

Methods: Endometrial aspiration was performed using Karman’s cannula in 100 cases who presented with abnormal uterine bleed, infertility and postmenopausal bleed. The endometrial specimens obtained by D&C were processed and evaluated histologically. The endometrial aspirated smears were reviewed for cytomorphological findings and were correlated with histopathological findings for diagnostic accuracy.

Results: Aspiration cytology is more specific for diagnosing malignant lesions (100%) while it is more sensitive for the benign conditions (85.06%) as compared to borderline lesions (complex and atypical hyperplasia), cytology also has higher NPV, PPV and Accuracy for malignant conditions as compared to the benign conditions

Conclusion: Endometrial aspiration technique with Karman’s cannula is simple, safe, cost effective and well tolerated outpatient procedure.

Keywords: Endometrial aspiration cytology, Cyclic endometrium, Dilatation   and Curettage, Endometrial malignancy, Karman’s cannula.