EFFICACY OF AUTOLOGOUS PLATELET RICH PLASMA IN COMPARISION WITH COLLAGEN GRANULE DRESSING IN CHRONIC NONHEALING ULCER

Abstract

Background & Method: The study was conducted in department of General Surgery, Index Medical College Hospital and Research Centre, Indore in a period of 12 months, in which 102 patients between 18 to 80 yr age having chronic non healing ulcer was taken. Out of which 51 patients received PRP and 51 patients received collagen granule dressing for 6weeks and followed for the outcome after 6 weeks.

Result: Both the PRP and collagen dressing are repeated once weekly for 6 weeks. At every week the ulcer area and volume is calculated and photographs are taken. Results are assessed at the end of 6weeks for the extent of wound closure on the basis of percentage change of the area and volume.

Conclusion: The result from study showed that PRP is safe and effective treatment with faster healing rates and takes less time to cover the ulcer area in comparison to collagen dressing. The difference between the outcome of 2 dressings was statistically significant (P value <0.05) A large population based study is needed to further consolidate the finding of the present study.

Keywords: autologous, platelet, plasma & collagen.