DEMOGRAPHIC PROFILE AND OUTCOMES OF ADVANCED EPITHELIAL OVARIAN CANCER

Abstract

Background: To study the epidemiological features and outcome of epithelial ovarian cancer patients treated at a tertiary care hospital.

Methods: We conducted a retrospective study at our institute to identify patients diagnosed with epithelial Ovarian Carcinoma (EOC) from 2013 to 2018. We studied the epidemiological profile and the outcome of the treatment in terms of response rates, Disease-free survival, and overall survival rates.

Results: A total of 238 patients were diagnosed with EOC over a period of 7 years. Out of 238 patients, complete pretreatment data was available for 197 patients. The median age at diagnosis was 59 years (range: 34–85 years). Totally 39 patients (16.38%) were younger than 45 years of age. The common presenting features were abdominal distension (82%), dysuria (43%), abdominal pain (40%), loss of appetite (36%), constipation (32%), shortness of breath (15%). serum CA125 levels were elevated in 73% cases at presentation

Conclusion: In conclusion, it is of extreme importance to identify the prognostic factors in patients with ovarian cancer to enable us to choose the most appropriate treatment strategy and to identify the risk of progression and death at follow-up. In our study, the patient age and FIGO clinical stage were the only independent prognostic factors reported.

Keywords: FIGO, Ovarian, Germ cell