STUDY THE RELATION BETWEEN SERUM SODIUM AND THE MODEL FOR END-STAGE LIVER DISEASE SCORE IN PATIENTS WITH LIVER CIRRHOSIS

Abstract

Background: The aim of the study was to evaluate the prevalence of hyponatremia in liver cirrhosis and the correlation between serum sodium and the Model for End-Stage Liver Disease (MELD) score in patients with liver cirrhosis.

Methods: We prospectively collected data of 200 patients of chronic liver disease hospitalized in medical and surgical gastroenterology department of Geetanjali medical college, Udaipur.

Results: Serum sodium values were strongly associated with severity of cirrhosis, assessed by child Pugh class and MELD score. There was significant relationship between serum sodium, renal function (as assessed by serum creatinine)

Conclusion: Hyponatremia is a common problem in liver cirrhosis, especially advanced cirrhosis. The study showed that there is an association between hyponatremia and the presence of certain complications of liver cirrhosis. Also hyponatremia was associated with a higher severity of cirrhosis assessed by MELD scores. 

Keywords: hyponatrenia, Liver cirrhosis, MELD score