TO SEE THE HISTO-PATHOLOGICAL PATTERN OF ORAL MUCOSAL LESIONS

Abstract

Background & Method: This prospective observational study was carried out with total number of patients 60 in the Department of Otorhinolaryngology and head and neck surgery, Amaltas Institute of Medical Sciences, Dewas, M.P., w.e.f. from August 2018 to September 2020. Patient was thoroughly investigated for complete haemogram, blood sugar, blood urea, serum creatinine, bleeding & Clotting time, coagulation profile, chest x-ray for any secondary focus.

Result: Out of 35 cases of clinically premalignant lesions 30 cases were positive for malignant cells on histology. 5 were suspicious for malignant cells. Out of the 25 cases of clinically malignant lesions 25 cases were positive for malignant cells on histology and nil cases of suspicious for malignancy. In this present study, on histopathology premalignant lesions was found in 8.33%   and malignancy was seen   91.66% cases. On histopathological examination, squamous cell carcinoma was the most common type among all cases (78.33%). In squamous cell carcinoma, keratinizing type was found in 33.33% and non- keratinizing type was found in 45%. Verrucous carcinoma was seen in 6.66% cases and verrucous hyperplasia was seen in 3.33% cases.

Conclusion: We Concluded in the study as diagnosed by histopathology were found premalignant in 8.33% and malignant 91.66% cases. The type of cancer was determined by histo-pathological examination after biopsy.  Squamous cell carcinoma was the most common type among all cases (78.33%). In squamous cell carcinoma, keratinizing type were found in 33.33% and non-keratinizing type were found in 45%, followed by verrucous carcinoma was seen in 6.66% cases, and verrucous hyperplasia was seen in 3.33% cases.

Keywords: Histo-pathological, Oral Mucosal Lesions.