THE STATUS OF LIPID PROFILE CONTROL IN CORONARY ARTERY DISEASE PATIENTS AT A TERTIARY CARE HOSPITAL

Abstract

Background: Patients of coronary artery disease require medical treatment to optimize their lipid profile. The present analysis evaluates the lipid profile among CAD patients receiving statin therapy. To study THE STATUS OF LIPID PROFILE CONTROL IN CORONARY ARTERY DISEASE PATIENTS AT A TERTIARY CARE HOSPITAL

Methods: Our study included 1016 patients with documented CAD by coronary angiography in Department of cardiology SMS medical college and associated group of hospitals. Patients treated with statin therapy for at least 3 months were included. We compared data relating to demographic parameters and other cardiovascular risk factors.

Results: In a total of 1016 patients (730 males and 286 females), (mean age 57.2 ±  8.8 years).

Complete lipid profiles of 1016 patients were recorded. Regarding the CAD patients with complete lipid profiles, 72% had lag in lipid profile control as against the current guidelines in at least one of the three main lipid parameters: low-density lipoprotein cholesterol (LDLc), high-density lipoprotein cholesterol (HDLc) and/or triglycerides. LDLc was not within target levels in 64.2% of these high risk patients; HDLc was abnormal in 35%, and triglycerides were elevated in 25% despite monthly follow up at the opd.

Conclusion: Most of the patients treated with statins, especially those with a high cardiovascular risk, do not meet recommended lipid targets and/or have a high frequency of abnormal HDLc and TG levels. The results of this study show that significant differences exist between the recommendations in the guidelines and clinical practice, as well as highlighting the need for a more intensive and integrated management of dyslipidemia in high-risk patients.

Keywords: Lipid profile, CAD, Lipoprotein