ASSESSMENT OF CLINICAL AND LABORATORY PARAMETERS IN TYPHOID FEVER IN PEDIATRIC CASES ADMITTED TO NMCH, PATNA

Abstract

India has a very high disease burden (214.2 per 1,00,000 individuals/year), primarily affecting children 5 to 15 years. Recently, there have been concerns of increasing proportion of infections in very young children, rising paratyphoid infections, and emerging drug resistance. Also, there are challenges in diagnosis and management of enteric fever due to lack of laboratory-based investigations. While blood culture remains the gold standard of diagnosis, the mainstays in developing countries are serological tests, which are suboptimal due to lack of standardization and uniformity. Hence based on above condition the present study was planned for Assessment of Clinical and Laboratory Parameters in Typhoid Fever in Pediatric Cases Admitted to NMCH, Patna.

The present study was planned in Department of Pediatrics, Nalanda Medical College and Hospital, Patna, Bihar, India. The study was planned from January 2018 to November 2018. In the present study 50 childrens of age up to 18 years having fever more than 7 days were enrolled. These cases were enrolled based on the Widal positive or positive culture were enrolled in the present study.

The data generated from present study concludes that Typhoid fever manifestations are diverse. The most common symptoms apart from fever were anorexia, vomiting, pain abdomen, diarrhoea followed by headache and cough. Also the Serum parameters are also seen changed in the Thyphoid affected patients. Typhoid fever remains a major public health problem in the developing countries predominantly seen in school going children among pediatric age group.

Keywords: Clinical, Laboratory Parameters, Typhoid Fever, Pediatric Cases, etc.