CORRELATION OF GLYCATED HAEMOGLOBIN WITH SERUM IRON, FERRITIN AND TIBC IN IRON DEFICIENCY ANEMIA

Abstract

Iron deficiency anemia is a common type of anemia — a condition in which blood lacks adequate healthy red blood cells. Red blood cells carry oxygen to the body's tissues. As the name implies, iron deficiency anemia is due to insufficient iron. HbA1c shows patient’s glycemic status of last 3 months. Some previous studies have been reported that iron deficiency anemia may increase the level of HbA1c.

AIM: To assess the status of HbA1c in patients of iron deficiency anemia & correlate HbA1c level with Serum Iron, Ferritin level.

MATERIALS AND METHODS: It is a cross sectional comparative study conducted in 1 yrs of duration. A total number of 60 subjects between the ages of 18 to 60 years were enrolled for the present study. Detailed medical history and relevant clinical examination data and written consent were obtained from all subjects by explaining the study procedure.

RESULTS: Haematological parameter like Hb, MCV, MCH, HCT and RDW were showed significantly difference in iron deficiency case and   control groups. Total haemoglobin, MCV, MCH, HCT were significantly reduced in IDA case group whereas there is increase RDW level in case group as compare to control (p<0.001).

CONCLUSION: There is negative correlation of HbA1c with Haemoglobin, Serum Iron and ferritin level whereas positive correlation is detected with TIBC. The correlation of HbA1c is found to be significant with serum iron and MCH.

Keywords: Hb, MCV, MCH, HCT and RDW