CLINICAL EVALUATION OF INTRAVENOUS IRON SUCROSE IN PREGNANT ANEMIC FEMALES

Authors

  • Aakarsh Sinha Senior Resident, Department of Obstetrics and Gynaecology, Madhubani Medical College and Hospital, Madhubani, Bihar, India.
  • Kumar Amit Senior Resident, Department of Paediatrics, Darbhanga Medical College and Hospital Laheriasarai, Darbhanga, Bihar, India.

DOI:

https://doi.org/10.32553/ijmbs.v4i1.1146

Abstract

The standard treatment in majority of the institutions is oral iron (OI), with blood transfusion reserved for severe or emergency cases. However, it is unreliable in the treatment of severe anemia. Blood transfusion has its own hazards, including transfusion of wrong blood and deadly infections like HIV, CMV, hepatitis and anaphylaxis. Thus, there is a need for a safe and effective alternative to OI or blood transfusion in the treatment of anemia. Iron dextran, the first parenteral iron used, lost its popularity due to anaphylaxis. Iron sucrose was then discovered as a parenteral iron that could be safe and effective. Hence based on above findings the present study was planned for Clinical Evaluation of Intravenous Iron Sucrose in Pregnant Anaemic Females.

The present study was planned in Department of Obstetrics and Gynaecology, Madhubani Medical College and Hospital, Madhubani, Bihar. In the present study 50 females presenting in antenatal clinic with haemoglobin between 5-9 g% were enrolled in the present study.  Iron sucrose (Injection Orofer S, Emcure Pharmacueticals Limited, India) was given in a dose of 200 mg intravenously twice weekly in 200 ml normal saline over a period of 15-20 min. First dose was given in the ward where equipment for cardiopulmonary resuscitation was available. The following doses were given on outpatient basis. Patients were observed for side effects or anaphylactic reactions. Any minor or major side effects were documented. All parameters were repeated at 2 wk interval till 8 wk.

The data generated from the present study concludes that intravenous iron sucrose therapy was effective to treat moderate anaemia in pregnant women. Intramuscular preparations are known to be associated with local side-effects. Iron sucrose complex iv therapy was with negligible side effects. It caused rapid rise in haemoglobin level and the replacement of stores was faster.

Keywords: Intravenous, Iron Sucrose, Pregnant, Anemic Females, etc.

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Published

2020-01-30

How to Cite

Sinha, A., & Amit, K. (2020). CLINICAL EVALUATION OF INTRAVENOUS IRON SUCROSE IN PREGNANT ANEMIC FEMALES. International Journal of Medical and Biomedical Studies, 4(1). https://doi.org/10.32553/ijmbs.v4i1.1146

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Section

Research Articles